Our group aims to understand how human memory is encoded, maintained, and retrieved through brain electrophysiological activity. We rely on intracranial electroencephalography (iEEG) recordings from patients with drug-resistant epilepsy. iEEG offers higher spatial resolution and signal quality than scalp electroencephalography (EEG) and is typically recorded in memory-related regions, such as the hippocampus, entorhinal cortex, and amygdala. We enhance iEEG recordings by using microelectrodes to capture activity from individual neurons, together with advanced algorithms to decode these neural signals and link them to cognitive processes. Our group also uses electrical stimulation to modulate brain activity during cognitive tasks, including closed-loop stimulation to pinpoint the relationship between specific electrophysiological patterns and cognition. Ultimately, our research aims to elucidate human memory dynamics and develop cognitive neuroprostheses capable of restoring memory function.

Dr. Davide Ciliberti
Cognitive Electrophysiology and Neurotechnology
